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Updated: Jan 29, 2026

Synthesis and Characterization of an Aspirin-fumarate Prodrug that Inhibits NFκB Activity and Breast Cancer Stem Cells
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欧洲议会议员途径:首次合成具有强烈抗菌活性的IspH导向产药

Alizée Allamand1,2, Ludovik Noël-Duchesneau1, Cédric Ettelbruck1

  • 1Laboratoire Chimie et Biochimie de Molécules Bioactives, Université de Strasbourg/CNRS, UMR 7177, Institut Le Bel, 4 rue Blaise Pascal, 67081 Strasbourg, France.

Microorganisms
|January 28, 2026
PubMed
概括

研究人员开发了针对MEP途径中的IspH酶的新型预药,用于治疗结核病. 替代化合物显示出显著的抗菌菌活性,表现优于异化.

关键词:
4-基-3-甲基-2-乙烯基二酸盐减少酶.这种细菌是Mycobacterium smegmatis.这是一种抗菌性抗菌体.循环烯基前药物 循环烯基前药物异化是什么 异化是什么异类生物合成异类生物合成

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