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根据白细胞计数驱动的山羊便微生物群的多样性分析

Meng Zeng¹, Hanlin Zhou¹, Qun Wu¹

¹Zhanjiang Experimental Station, Chinese Academy of Tropical Agricultural Sciences, Zhanjiang 524013, China.

|January 28, 2026

概括

海南黑山羊的白细胞 (WBC) 计数与肠道微生物群组成相关. 较高的白细胞计数与增加的微生物多样性和特定的细菌属有关,这表明肠道健康和免疫之间存在联系.

科学领域:

动物科学动物科学
微生物学微生物学
免疫学免疫学免疫学

背景情况:

莱州山羊是一种重要的本土品种,由于可变的弹性,在疾病监测方面面临着挑战.
白血细胞 (WBC) 计数是免疫状况的关键指标,但其与这种品种肠道微生物群的联系尚不清楚.

研究的目的:

根据外围WBC计数,对海南黑山羊的便微生物群进行表征.
为了研究WBC数量与山羊肠道微生物群落结构之间的关联.

主要方法:

羊被分为低,中和高WBC计数组.
用测序分析了便微生物群的组成和多样性.
通过LEfSe和Spearman的相关性分析,确定了特定的微生物种群及其与WBC数量的关联.

主要成果:

在WBC组之间发现了α和β多样性的显著差异,高WBC组表现出更大的丰富性.
肠道微生物群主要由Bacillota和Bacteroidota组成.
在高WBC群中,包括Ruminococcus在内的特定属得到了丰富.
白血球数量与未分类_f_Oscillospiraceae和未分类_c_Clostridia的丰度正相关.

结论:

白细胞计数与海南黑山羊的独特肠道微生物群落有显著的关联.
与WBC计数相关的微生物生物标志物表明肠道微生物组与宿主免疫调节之间的联系.
这些发现为山羊中介微生物群的健康评估提供了基础.

关键词:

莱州山羊 - 莱州山羊血液参数血液参数便中的微生物白细胞是白细胞的组成部分.

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