积极推进的微型机器人用于泌尿疾病的药物输送
Chunlian Zhong1,2, Menghuan Tang3, Zhaoqing Cong1,2
1Department of Urology, Stony Brook University, Stony Brook, NY 11794, USA.
Micromachines
|January 28, 2026
概括
积极的微型机器人 (MRs) 在尿道中提供自主导航,克服了被动系统的局限性. 本综述探讨了它们在治疗结石和膀癌方面的潜力,提高了药物输送和诊断.
科学领域:
- 生物医学工程 生物医学工程
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 机器人技术 机器人技术 机器人技术
背景情况:
- 积极推进的微型机器人 (MRs) 提供自主移动性,用于精确的组织透,与被动系统不同,受扩散限制.
- 尿路的可访问性和充满液体的性质使其成为微机器人干预的理想选择.
- 核磁共振可以解决治疗结石和膀癌治疗的局限性.
研究的目的:
- 为泌尿病学中微型机器人技术提供全面的分析.
- 探索MR如何克服尿路中关键的治疗挑战.
- 评估微机器人干预在泌尿病学中的临床转化.
主要方法:
- 尿道环境的推进机制的分类 (例如,尿素燃料纳米电机,磁性群).
- 详细审查新兴应用程序,如可生物吸收的声学机器人和磁.
- 对临床翻译的挑战进行批判性评估,包括生物相容性和跟踪.
主要成果:
- 微型机器人可以通过各种能源 (化学,声学,磁性) 来推进有针对性的交付.
- 特定的推进方法被优化为尿道内的独特条件.
- 新兴应用包括瘤切除和微创活检.
结论:
- 微型机器人对彻底改变泌尿治疗有着重大前景.
- 临床翻译必须解决生物相容性,实时跟踪和调节方面的挑战.
- 进一步的研究和开发对于实现微机器人在泌尿病学中的全部潜力至关重要.
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