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相关概念视频

Ionization Energy03:12

Ionization Energy

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The amount of energy required to remove the most loosely bound electron from a gaseous atom in its ground state is called its first ionization energy (IE1). The first ionization energy for an element, X, is the energy required to form a cation with 1+ charge:
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Bioavailability Study Design: Single Versus Multiple Dose Studies01:11

Bioavailability Study Design: Single Versus Multiple Dose Studies

228
Bioavailability studies are essential for understanding how a drug is absorbed, distributed, metabolized, and excreted in the body. These studies assess the extent and rate at which the active pharmaceutical agent becomes available at the site of action. The design of bioavailability studies can involve single-dose or multiple-dose regimens, each with distinct advantages and limitations.Single-dose studies are the preferred approach due to their simplicity and reduced drug exposure for...
228
Dose Size and Dosing Frequency: Determination Methods01:21

Dose Size and Dosing Frequency: Determination Methods

288
Determining the optimal dose size and dosing frequency in pharmacotherapy is crucial for achieving therapeutic effectiveness while minimizing adverse effects. This article explores the methodologies employed in determining these parameters, focusing on their significance and interplay to tailor dosing regimens.Dose Size: Dose size refers to the amount of a drug administered in a single dose. It is determined based on the drug's pharmacodynamics and pharmacokinetics properties and...
288
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses01:25

Determination of Multiple Dosing Parameters: Loading and Maintenance Doses

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A loading dose is an essential pharmacological strategy to rapidly achieve the target plasma drug concentration necessary for an immediate therapeutic effect. This approach is especially critical for drugs characterized by slow absorption or extended half-lives, where delaying therapeutic plasma levels could compromise treatment outcomes. By administering a loading dose, clinicians ensure a prompt onset of drug action, even for agents with complex pharmacokinetic profiles.Achieving steady-state...
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Rational Dosage Regimen: Maintenance Dose and Loading Dose01:24

Rational Dosage Regimen: Maintenance Dose and Loading Dose

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A rational dosage regimen considers a drug's pharmacokinetics, including its absorption, distribution, metabolism, and elimination from the body. By understanding these factors, the appropriate dosage can be determined, and the dosing schedule can be designed to achieve and maintain the desired therapeutic effect while minimizing adverse effects.
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
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Chemical Ionization (CI) Mass Spectrometry01:21

Chemical Ionization (CI) Mass Spectrometry

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The molecular ion peak of a molecule in the mass spectrum provides vital information for molecular identification. However, conventional electron impact ionization can lead to the rapid dissociation of some molecular ions before they reach the detector. A milder ionization method is required to increase the lifetime of such ionized analyte molecules. Chemical ionization (CI) is a gas-phase protonation reaction useful for mass-analyzing analyte molecules that are easily protonated to yield the...
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相关实验视频

Updated: Jan 29, 2026

Evaluation of the Impact of a New Cooling Cell Processor System on Islet Cell Isolation Facility
05:21

Evaluation of the Impact of a New Cooling Cell Processor System on Islet Cell Isolation Facility

Published on: August 11, 2023

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在130nm CMOS 处理器上进行总电离剂量效应模拟研究.

Yi Liu1, Yuchen Liu2, Xinfang Liao3

  • 1Shenzhen Institute of Technology, Xidian University, Shenzhen 518000, China.

Micromachines
|January 28, 2026
PubMed
概括
此摘要是机器生成的。

这项研究模拟了对130nm LEON2处理器的总电离剂量 (TID) 影响. 它揭示了处理器的故障值和机制,指导大量CMOS处理器的设计辐射硬化 (RHBD).

关键词:
130 纳米大批量CMOS失效值是指一个失效值.处理器的处理器.在系统层面进行模拟.总的电离剂量效应的电离剂量效应.

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Evaluation of the Impact of a New Cooling Cell Processor System on Islet Cell Isolation Facility

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科学领域:

  • 半导体设备物理学 半导体设备物理
  • 电子产品中的辐射效应.
  • 集成电路设计 集成电路设计

背景情况:

  • 总电离剂量 (TID) 影响对微电子设备的可靠性构成重大威胁.
  • 了解晶体管中TID诱导的泄漏电流对于预测系统级故障至关重要.
  • 在各种应用中广泛使用SMIC 130nm批量CMOS技术,需要进行辐射性能分析.

研究的目的:

  • 在SMIC 130nm LEON2处理器上对TID效应进行系统级模拟.
  • 为NMOS晶体管开发一个紧的模型,考虑TID诱导的泄漏电流.
  • 为了确定处理器的故障值,故障机制和电源电流在辐射下的行为.

主要方法:

  • 使用Sentaurus TCAD进行130nm NMOS晶体管的设备级模拟.
  • 为TID诱导的泄漏电流开发一个Verilog-A紧型号.
  • 将紧型号集成到SPICE网络列表中,用于LEON2处理器的系统级模拟.

主要成果:

  • 该研究确定了在TID.下LEON2处理器的故障值和故障机制.
  • 观察到电源电流随着辐射剂量的增加而增加.
  • 开发的紧型号准确地描述了NMOS晶体管中TID诱导的泄漏电流.

结论:

  • 系统级模拟方法为130nm批量CMOS处理器的辐射性能提供了宝贵的见解.
  • 这些发现可以指导辐射性能评估和实施辐射硬化通过设计 (RHBD) 策略.
  • 准确的紧型建模对于预测系统级辐射效应至关重要.