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基于14年脏活检材料的病态的发生率和相关性:波兰的一项回顾性单中心研究
Krzysztof Benc1, Ewa Tabaka1, Wiktoria Pabian1
1Department of Nephrology, Transplantation Medicine and Internal Diseases Institute of Internal Diseases, Wroclaw Medical University, 50-556 Wroclaw, Poland.
Journal of clinical medicine
|January 28, 2026
概括
波兰的脏活检诊断显示出转变,IgA脏病和FSGS最常见. 狼性炎主要影响女性,而老年患者患有粉样性粉症和血管炎.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 临床病理学 临床病理学
- 流行病学 流行病学
背景情况:
- 波兰经历了活检率和诊断模式的变化.
- 这些变化与不断发展的医疗实践,诊断工具和疾病流行率有关.
- 了解这些趋势对于治疗病至关重要.
研究的目的:
- 分析波兰脏活检频率和诊断模式的时间趋势.
- 评估不同年龄组和性别的活检诊断.
- 将研究结果与之前的国家和国际研究进行比较.
主要方法:
- 在2010年至2024年期间在一所大学医院进行的1969次脏活检的回顾性分析.
- 排除了移植受体,重点是1291个本地细胞活检.
- 诊断与患者人口统计 (年龄,性别),糖尿病状况和时间的相关性.
主要成果:
- 脏活检数量增加,在2021年达到顶峰. 40-64岁的年龄组接受了大多数活检,老年患者的比例越来越高.
- 最常见的诊断是IgA脏病 (IgAN),焦点细分细胞凝结症 (FSGS) 和狼性炎.
- 老年患者的amyloidosis,FSGS,血管炎和膜性脏病发病率较高. 狼性炎在女性中明显更常见.
结论:
- 这项研究强调了波兰不断发展的病诊断,Igan,FSGS和狼性炎是关键诊断.
- 在老年人群中和按性别出现不同的诊断模式,特别是狼性炎.
- 进一步的多中心研究对于解决慢性病 (CKD) 诊断不足和提高波兰公众意识至关重要.
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