阻抗问题及其原因 - 一个单一中心对601名患者进行De Novo深度大脑刺激的分析
Thomas Fortmann1,2,3, Samer Zawy Alsofy2,3, Antonio Santacroce2,3,4
1Department of Stereotactic Neurosurgery, St. Barbara Hospital Hamm, 59073 Hamm, Germany.
Journal of clinical medicine
|January 28, 2026
概括
深度大脑刺激 (DBS) 硬件修订不常见 (4.16%),通常是由于电极问题. 震患者和较旧的Medtronic系统显示阻抗异常的修订率更高.
科学领域:
- 神经外科 神经外科
- 生物医学工程 生物医学工程
- 神经学 神经学
背景情况:
- 深度大脑刺激 (DBS) 需要持续的患者管理.
- DBS治疗效果的突然丧失经常与阻抗异常有关.
- 如果重编程失败,可能需要对硬件缺陷进行修复手术.
研究的目的:
- 确定DBS患者的大队伍中阻抗异常的发生率和原因.
- 分析不同患者诊断和DBS硬件制造商的修复手术率.
主要方法:
- 对601名接受了新的DBS植入的患者的回顾性分析.
- 系统评估阻抗异常和修复手术的原因.
- 在修改案例中分析制造商,电极和接触者的参与.
主要成果:
- 601名患者中有25名 (4.16%) 需要因阻抗异常而进行修复手术.
- 与帕金森病 (2.67%) 或 dystonia (5.71%) 相比,在患者 (6.19%) 中观察到更高的修订率.
- 梅特罗尼克系统的修订率最高 (7.6%),艾伯特的3.4%和波士顿科学公司的0%;电极问题是主要原因 (19/25).
结论:
- 在DBS中需要修改手术的阻抗异常相对较少.
- 与电极相关的问题是硬件故障的主要原因.
- 修订率因患者指示和DBS系统制造商而异,较旧的系统和特定电极类型的发生率较高.
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