紫外线辐射对Mpox病毒污染的表面的有效性
Anna Gidari1, Samuele Sabbatini2, Carlo Pallotto1
1Department of Medicine and Surgery, Clinic of Infectious Diseases, "Santa Maria della Misericordia" Hospital, University of Perugia, 06132 Perugia, Italy.
低剂量的紫外线辐射可以有效地使Mpox病毒 (MpoxV) 在常见的表面上失活. 这种消毒方法有望在各种环境中防止MpoxV的间接传播.
科学领域:
- 病毒学 病毒学
- 环境科学 环境科学
- 传染病控制和控制传染病
背景情况:
- 全球Mpox病毒 (MpoxV) 疫情正在增加,引发人们对传播途径的担忧.
- 虽然密切接触是主要的,但怀疑MpoxV的传染是来自虫.
- 需要有效的消毒策略来控制MpoxV的传播.
研究的目的:
- 评估紫外线辐射对MpoxV在受污染的表面上的失活效果.
- 为了确定MpoxV消毒的最佳UV-C剂量.
主要方法:
- 在塑料,玻璃和不钢上对MopoxV进行了UV-C (254nm) 辐射.
- 使用TCID50和暴露后的斑块检测量病毒标位.
- 测试了增加的UV-C剂量以确定杀毒活性.
主要成果:
- 6.34mJ/cm2的UV-C剂量显著降低了所有测试表面上的MpoxV负载 (>2-log降低).
- 根据材料的有效失活剂量 (EC90) 有所不同: 3.33 mJ/cm2 (塑料), 0.81 mJ/cm2 (不钢), 1.98 mJ/cm2 (玻璃).
- 在有效剂量的塑料和不钢上没有检测到可活性的病毒.
结论:
- 紫外线-C辐射是一种高效的方法,可以在矿上使MpoxV无活化.
- 低剂量的紫外线可以快速消毒表面,支持环境控制策略.
- 紫外线消毒可以帮助防止在医疗保健和社区环境中间接传播MpoxV.
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