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单克隆抗体的口服生物可用性

Ashwni Verma1, Shengjia Wu1, Dhaval K Shah1

  • 1Department of Pharmaceutical Sciences, School of Pharmacy and Pharmaceutical Sciences, The State University of New York at Buffalo, Buffalo, NY 14214, USA.

Pharmaceutics
|January 28, 2026
PubMed
概括

在动物中,单克隆抗体 (mAbs) 的口服生物利用率约为0.02%. 这项临床前研究为mAb提供了第一个绝对的口服生物可用性值,表明口服后系统吸收非常低.

关键词:
抗体是一种抗体.口服生物可用性 口服生物可用性药物动力学 (PK) 是指

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