相关实验视频

Updated: Jan 29, 2026

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery
05:44

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery

Published on: November 14, 2018

21.2K

通过鼻至大脑途径对药物开发的新见解:通过神经系统疾病的多基克reatine Ester进行示例化

Henri Benech1, Victoria Flament1, Clara Lhotellier1

  • 1Ceres Brain Therapeutics, Institut du Cerveau ICM, Hôpital de la Pitié-Salpêtrière, 47 Bd de l'Hôpital, 75013 Paris, France.

Pharmaceutics
|January 28, 2026
PubMed
概括

通过鼻至大脑通道进行鼻内药物输送,可以直接进入神经元,绕过血脑屏障. 这篇评论批判性地评估了开发这种有前途的大脑疾病途径的工业因素.

关键词:
鼻子到大脑的连接骨髓缩侧面硬化症 (ALS) 是一种血脑屏障 血脑屏障 血脑屏障 血脑屏障肌酸载体缺乏症 肌酸载体缺乏症十二基克reatine Ester 是一种多基克reatine .药物输送是药物输送的过程.这是一种鼻腔内科的治疗方法.神经系统疾病 神经系统疾病

更多相关视频

Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry10:58

Targeted Neuronal Injury for the Non-Invasive Disconnection of Brain Circuitry

Published on: September 27, 2020

5.5K
Ex vivo Culturing of Whole, Developing Drosophila Brains08:39

Ex vivo Culturing of Whole, Developing Drosophila Brains

Published on: July 27, 2012

13.6K

相关概念视频

Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
1.1K
Antiepileptic Drugs: GABAergic Pathway Potentiators01:18

Antiepileptic Drugs: GABAergic Pathway Potentiators

γ-aminobutyric acid or GABA, plays a pivotal role as an inhibitory neurotransmitter in the brain. GABA pathway potentiators, also known as GABAergic drugs, are a class of pharmaceutical agents designed to enhance the functioning of the GABAergic system. These medications primarily treat epilepsy, a neurological disorder characterized by recurrent seizures.
The key GABA pathway potentiators used in epilepsy management are as follows.
Benzodiazepines are a well-known class of drugs used for...
1.3K
Drugs Used in Upper Respiratory Disorders: Overview01:16

Drugs Used in Upper Respiratory Disorders: Overview

Upper respiratory tract disorders, including viral infections and allergic rhinitis, cause significant discomfort and disrupt daily life. Managing these conditions involves a variety of drugs, such as antihistamines, intranasal steroids, decongestants, antitussives, expectorants, and mucolytics. Specific examples of drugs in each category are provided.
Antihistamines (e.g., Benadryl) block histamines from binding. Histamines are chemicals released during an allergic reaction in the body. As a...
654
Nose and Nasal Cavity01:24

Nose and Nasal Cavity

The nose is composed of an observable exterior segment (external nose) and an internal segment within the skull known as the nasal cavity (internal nose). The external nose, visible on the face, consists of a framework of bone and hyaline cartilage enveloped in skin and muscle and lined with a mucous membrane. This structure is supported by the frontal bone, nasal bones, and maxillary bone and is supplemented by a cartilaginous framework comprising the septal nasal cartilage, lateral nasal...
11.5K
Neurons as Communicators of the Brain01:22

Neurons as Communicators of the Brain

Neurons, the fundamental units of the brain and nervous system, function as the primary transmitters of information throughout the body. Their ability to communicate through electrical and chemical signals is vital for every bodily function, from regulating the heartbeat to processing complex thoughts. Each neuron has three main components: the cell body (soma), dendrites, and an axon, each specialized to facilitate swift and efficient neural communication.
Cell Body
The cell body, also known...
3.1K
C4 Pathway and CAM01:27

C4 Pathway and CAM

Most plants use the C3 pathway for carbon fixation. However, some plants, such as sugar cane, corn, and cacti that grow in hot conditions, use alternative pathways to fix carbon and conserve energy loss due to photorespiration. Photorespiration is the process that occurs when the oxygen concentration is high. Under such conditions, the rubisco enzyme in the Calvin cycle binds O2 instead of CO2, which halts photosynthesis and consumes energy.
C4 Pathway
The C4 pathway is used by plants such as...
49.1K