食品中的益生菌和生物活性化合物:从抗氧化特性到肠道微生物群调节
Berta Gonçalves1, Alice Vilela2, Alfredo Aires1
1Centre for the Research and Technology of Agro-Environmental and Biological Sciences (CITAB), Institute for Innovation, Capacity Building and Sustainability of Agri-Food Production (Inov4Agro), University of Trás-of-Montes e Alto Douro, Quinta de Prados, 5000-801 Vila Real, Portugal.
Molecules (Basel, Switzerland)
|January 28, 2026
概括
来自植物和发酵食品的食生物活性化合物提供了广泛的健康益处. 它们的有效性由肠道微生物增强,但个性化营养仍然存在生物可用性挑战.
科学领域:
- 营养科学 营养科学
- 微生物学 微生物学
- 食品科学 食品科学 食品科学
背景情况:
- 来自植物和发酵食品的饮食生物活性化合物对健康产生性作用,包括抗氧化,抗炎,心脏保护,神经保护和代谢益处.
- 发酵食品提供微生物衍生代谢物和益生菌,增强营养物质的生物可用性和肠道健康.
- 肠道微生物群调解饮食中的生物活性效应,通过双向相互作用和代谢物产生影响宿主健康.
研究的目的:
- 为食品衍生生物活性化合物和益生菌介导作用的来源,机制和对健康的影响提供综合的视角.
- 突出当前在饮食生物活性物质的临床应用中的翻译挑战.
- 探索未来发展有效的功能性食品和个性化的营养策略的方向.
主要方法:
- 关于饮食中的生物活性化合物,发酵食品,肠道微生物群及其对健康的影响的现有文献的审查.
- 对作用机制的分析,包括抗氧化,抗炎和代谢作用.
- 检查影响生物可用性和宿主微生物相互作用的因素.
主要成果:
- 饮食中的生物活性和益生菌通过肠道微生物群协同调节宿主健康.
- 微生物的新陈代谢将食化合物转化为有益的代谢物,如短链脂肪酸.
- 低生物可用性,受消化,食物矩阵,宿主遗传学和微生物群的影响,限制了临床转化.
结论:
- 了解生物活性,益生菌和代谢物之间的协同相互作用对于克服生物可用性限制至关重要.
- 需要进一步的研究来开发有效的功能性食品和基于这些相互作用的个性化营养策略.
- 饮食中的生物活性和益生菌具有显著的潜力,可以改善基本营养之外的人类健康.
相关概念视频
01:23Properties of Organometallic Compounds
1.7K
Organometallic compounds are compounds that contain a carbon–metal bond. Carbon belongs to an organyl group like alkyl, aryl, allyl, or benzyl groups. The metal can be from Group I or Group II of the periodic table, a transition metal, or a semimetal.
1.7K
03:02Organic Compounds
57.2K
All living things are formed mostly of carbon compounds called organic compounds. The category of organic compounds includes both natural and synthetic compounds that contain carbon. Although a single, precise definition has yet to be identified by the chemistry community, most agree that a defining trait of organic molecules is the presence of carbon as the principal element, bonded to hydrogen and other carbon atoms. However, some carbon-containing compounds such as carbonates, cyanides, and...
57.2K
02:38Molecules and Compounds
68.6K
Atoms and Molecules
68.6K
01:27Elements and Compounds
104.2K
Pure substances consist of only one type of matter. A pure substance can be an element or a compound. An element consists of only one type of atom, while a compound consists of two or more types of atoms held together by a chemical bond.
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
Elements
Elements are classified as atomic or molecular based on the nature of their basic units. They are unique forms of matter with specific chemical and physical properties that cannot break down into smaller substances by ordinary chemical reactions. There...
104.2K
01:30Regulation of Food Intake
2.8K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
2.8K
02:55Solubility of Ionic Compounds
68.1K
Solubility is the measure of the maximum amount of solute that can be dissolved in a given quantity of solvent at a given temperature and pressure. Solubility is usually measured in molarity (M) or moles per liter (mol/L). A compound is termed soluble if it dissolves in water.
68.1K