通过CHPTAC系统的新型多电离子阿拉比诺甲衍生物:结构,特性和抗氧化活性
Maria V Sereda1,2, Yuriy N Malyar1,2, Valentina S Borovkova1,2
1Institute of Chemistry and Chemical Technology, Krasnoyarsk Science Center, Siberian Branch Russian Academy of Sciences, Akademgorodok 50/24, Krasnoyarsk 660036, Russia.
性阿拉比诺 (AG) 衍生物被合成,具有增强的抗氧化能力. 最佳的四级化条件被确定为pH12,50°C和31.6小时,产生有价值的功能材料.
科学领域:
- 聚合物化学 聚合物化学
- 材料科学 材料科学 材料科学
- 生物化学 生物化学
背景情况:
- 阿拉比诺 (AG) 是一种具有潜在应用的天然多糖体.
- 修改AG可以增强其各种用途的功能性质.
- 四方化引入了阴离子组,改变了多糖的特性.
研究的目的:
- 为了合成阴阳性阿拉比诺 (AG) 衍生物.
- 调查四级化对AG特性的影响.
- 评估修改AG的抗氧化能力.
主要方法:
- 使用 (3-Chloro-2-hydroxypropyl) -trimethylammonium化物 (CHPTAC) 的AG的以太化.
- 通过pH和反应时间控制置换度 (DS).
- 使用元素分析,GPC,FTIR,1H NMR和TGA进行表征.
- 通过DPPH自由基清除试验评估的抗氧化活性.
主要成果:
- 成功制备了具有从0.02到0.19的DS的阴离子AG衍生品.
- 确定了最佳的四级化条件:pH12,50°C和31.6小时.
- 与未经修改的AG相比,四分化AG表现出更好的抗氧化能力.
- 观察到具有延长反应时间的水解副作用.
结论:
- 该研究成功地产生了具有可调节性质的阴离子AG衍生物.
- 优化的合成条件提高了四级化的效率.
- 修改后的AG显示出作为抗氧化剂的前景.
- 了解反应动力学至关重要,以尽量减少副作用.
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