LDT10LDT119,,Trypanosoma cruzi

Renato Granado1,2, Brenda de Lucena Costa3, Cleonice Andrade Holanda3

  • 1Laboratório de Ultraestrutura Celular Hertha Meyer, Instituto de Biofísica Carlos Chagas Filho, Universidade Federal do Rio de Janeiro, Centro de Ciências da Saúde, Bloco G, Ilha do Fundão, Rio de Janeiro 21941-900, RJ, Brazil.

概括

两种新型卡达诺基衍生的脂类比物LDT10和LDT119,对夏加斯病的所有阶段 (由Trypanosoma cruzi引起) 具有强烈的活性,具有低毒性. 这些化合物来源于果仁贝液体,代表了新的查加斯病治疗的有希望的候选人.

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