绘制自闭症谱系障碍的全球研究趋势:药理学和药学研究的文献分析
Gianfranco Sabadini1, Angelina Palacios-Muñoz2,3, Isaac E García2,3
1Instituto de Química, Facultad de Ciencias, Universidad de Valparaíso, Av. Gran Bretaña 1111, Valparaíso 2360102, Chile.
Pharmaceuticals (Basel, Switzerland)
|January 28, 2026
概括
本文献分析揭示了自闭症谱系障碍 (ASD) 药理学研究的指数级增长. 关键领域包括神经生物学,氧化应激和新的治疗干预措施,突出显示了向精准医学的转变.
科学领域:
- 药理学和制药科学 药理学和制药科学
- 神经发育研究 神经发育研究
背景情况:
- 自闭症谱系障碍 (ASD) 在神经学研究中提出了重大挑战.
- 关于自闭症的药理学研究正在迅速扩大.
- 缺乏对出版趋势,主要贡献者和主题发展的全面概述.
研究的目的:
- 对ASD的药理学研究进行全面的文献分析.
- 分析2001年至2025年的出版物.
主要方法:
- 从科学网络 (WoS) 数据库 (JCR药房和药理学类别) 中分析了1170篇文章.
- 使用了VOSviewer和图书法规 (普莱斯,布拉德福德,齐夫,洛特卡).
- 检查了出版物增长,h指数,作者,机构/国家生产力和关键词的同时出现.
主要成果:
- 在过去二十年中,ASD药理学研究的指数增长.
- 贡献最多的国家:美国,中国,意大利.
- 领先的机构:沙特国王大学,哈佛医学院,俄俄州立大学.
- 关键词:自闭症谱系障碍,瓦尔酸,氧化应激,黄酸,表明神经生物学,氧化还原失衡和疗法之间的联系.
- 新兴的研究主题:免疫突触相互作用,微生物群,生物标志物引导的方法.
结论:
- 在ASD药理学研究中的全球扩张和多样化.
- 转向综合生物框架和以精度为导向的战略.
- 强调需要跨学科的合作,以改善ASD的翻译结果.
相关概念视频
Autism Spectrum Disorder
1.1K
Autism spectrum disorder (ASD) is a neurodevelopmental condition marked by persistent deficits in social communication and interaction alongside restrictive and repetitive behaviors or interests. ASD is sometimes accompanied by intellectual impairment.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
1.1K
The Electromagnetic Spectrum
65.1K
The electromagnetic spectrum consists of all the types of electromagnetic radiation arranged according to their frequency and wavelength. Each of the various colors of visible light has specific frequencies and wavelengths associated with them, and you can see that visible light makes up only a small portion of the electromagnetic spectrum. Because the technologies developed to work in various parts of the electromagnetic spectrum are different, for reasons of convenience and historical...
65.1K
The Electromagnetic Spectrum
33.6K
Electromagnetic waves are categorized according to their wavelengths and frequencies, giving the electromagnetic spectrum. These waves are classified as radio, infrared, ultraviolet, etc. Radio waves refer to electromagnetic radiation with wavelengths ranging from millimeters to kilometers. Radio waves are commonly used for audio communications (i.e., radios) and typically result from an alternating current in the wires of a broadcast antenna. They cover a broad wavelength range and are used...
33.6K
Global Climate Change
28.9K
Throughout its ~4.5 billion year history, the Earth has experienced periods of warming and cooling. However, the current drastic increase in global temperatures is well outside of the Earth’s cyclic norms, and evidence for human-caused global climate change is compelling. Paleoclimatology, the study of ancient climate conditions, provides ample evidence for human-caused global climate change by comparing recent conditions with those in the past.
28.9K
IR Spectrum
2.1K
When infrared (IR) radiation passes through a molecule, the bonds stretch or bend by absorbing the radiation. This absorption creates the molecule's absorption spectrum, which is the plot of its percentage transmittance versus wavenumber.
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
2.1K
Current Trends in Nursing I
5.4K
Current trends in nursing include:
5.4K


