相关实验视频
Updated: Jan 29, 2026

06:15
Preparation of Binary and Ternary Deep Eutectic Systems
Published on: October 31, 2019
12.7K
卡普里克酸为基础的治疗深度美容系统:在深度美容溶剂框架内进行专注的审查
Faisal Al-Akayleh1, Ahmed S A Ali Agha2, Ali R Olaimat3
1Faculty of Pharmacy and Medical Sciences, University of Petra, Amman 11196, Jordan.
Pharmaceuticals (Basel, Switzerland)
|January 28, 2026
概括
基于酸 (CA) 的治疗性深层浸泡系统 (THEDES) 提高了药物的溶解性,透性和生物活性. 这些绿色配方为药物输送提供了一个新的平台,尽管稳定性和监管方面需要进一步调查.
科学领域:
- 制药科学 制药科学
- 材料科学 材料科学 材料科学
- 药物输送系统 药物输送系统
背景情况:
- 基于酸 (CA) 的治疗性深层体系统 (THEDES) 是新的生物功能矩阵.
- 这些系统显示出改善药物溶解,透性和生物活性的潜力.
研究的目的:
- 对CA-THEDES的设计,机制和制药性能进行审查和综合证据.
- 确定CA-THEDES的统一原则和未来研究方向.
主要方法:
- 针对性的数据库搜索进行,以确定有关CA-THEDES的相关研究.
- 对已识别的研究进行选,重点关注其设计,机制和制药性能.
主要成果:
- CA-THEDES通过结和无形化来增强药物溶解性.
- 由于CA的两链,观察到改善的通过皮肤和通过粘膜的透.
- CA表现出协同作用的抗微生物和抗癌作用,作为辅助疗法.
- 在长期稳定性,毒理学和监管分类中发现了差距.
结论:
- CA-THEDES提供了一个合理设计的平台,用于下一代药物输送.
- 这些系统在单一的绿色配方中将溶剂功能与治疗活性相结合.
- 人工智能/ML方法可以帮助合理选择和优化CA-THEDES.
相关概念视频
Solvents
70.8K
A solvent is a substance, most often a liquid, that can dissolve other substances. Here, the substance being dissolved is called a solute. When a solvent and a solute combine, they form a solution - a homogenous mixture of both the solvent and the solute. Water is a universal biological solvent. Its polar structure allows it to dissolve many other polar compounds. The ability of water to dissolve is governed by a balance between water molecules binding to each other and binding to the solute.
A...
A...
70.8K
Techniques of Therapeutic Communication II: Focusing, Paraphrasing, and Summarizing
11.4K
Focusing involves centering a conversation on a message's critical elements or concepts. Focusing is valuable if the talk is vague or patients begin to repeat themselves. Sometimes, when patients are asked about their symptoms, they may go off-topic and try to tell their entire life story. Respectfully, the nurse should bring the conversation back into focus.
This therapeutic technique can also be used when a patient brings up pertinent information during a health-related conversation. The...
This therapeutic technique can also be used when a patient brings up pertinent information during a health-related conversation. The...
11.4K
Lewis Acids and Bases
48.3K
In 1923, G. N. Lewis proposed a generalized definition of acid-base behavior in which acids and bases are identified by their ability to accept or to donate a pair of electrons and form a coordinate covalent bond.
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
A coordinate covalent bond (or dative bond) occurs when one of the atoms in the bond provides both bonding electrons. For example, a coordinate covalent bond occurs when a water molecule combines with a hydrogen ion to form a hydronium ion. A coordinate covalent bond also results when...
48.3K
Ions as Acids and Bases
26.3K
Salts with Acidic Ions
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
Salts are ionic compounds composed of cations and anions, either of which may be capable of undergoing an acid or base ionization reaction with water. Aqueous salt solutions, therefore, may be acidic, basic, or neutral, depending on the relative acid-base strengths of the salt’s constituent ions. For example, dissolving the ammonium chloride in water results in its dissociation, as described by the equation:
26.3K
Bronsted-Lowry Acids and Bases
104.7K
The acid-base reaction class has been studied for quite some time. In 1680, Robert Boyle reported traits of acid solutions that included their ability to dissolve many substances, to change the colors of certain natural dyes, and to lose these traits after coming in contact with alkali (base) solutions. In the eighteenth century, it was recognized that acids have a sour taste, react with limestone to liberate a gaseous substance (now known to be CO2), and interact with alkalis to form neutral...
104.7K
Acids, Bases and Neutralization Reactions
63.7K
An acid-base reaction is one in which a hydrogen ion, H+, is transferred from one chemical species to another. Such reactions are of central importance to numerous natural and technological processes, ranging from the chemical transformations within cells or lakes and oceans to the industrial-scale production of fertilizers, pharmaceuticals, and other substances essential to the society.
63.7K

