患有慢性病的儿童接种疫苗:现状和前景
Maria Bitsori1, Maria Michailou1, Emmanouil Galanakis1,2
1Department of Paediatrics, Heraklion University Hospital, 71500 Crete, Greece.
Vaccines
|January 28, 2026
概括
患有慢性病 (CKD) 的儿童的疫苗接种率较低,增加了感染风险. 在他们的护理中优先进行免疫接种对于更好地预防疫苗可预防的疾病至关重要.
科学领域:
- 儿科脏病学 儿科脏病学
- 免疫学 免疫学 免疫学
- 公共卫生 公共卫生
背景情况:
- 患有慢性病 (CKD) 的儿童因免疫力受损和治疗而面临更高的感染风险.
- 在这个脆弱的儿科群体中,低于最佳的疫苗接种率有助于增加发病率和死亡率.
研究的目的:
- 审查疫苗可预防的感染率和患有CKD的儿童的疫苗接种覆盖率.
- 确定他们脆弱和疫苗接种程度低的原因.
- 探索改善疫苗接种覆盖率和预防感染的策略.
主要方法:
- 对有关儿童慢性瘤疫苗接种覆盖率和感染发病率的现有文献进行系统审查.
- 对调查慢性病儿童免疫反应的研究进行分析.
- 评估提议的干预措施,以提高接种疫苗的坚持.
主要成果:
- 现有的数据虽然有限,但始终显示,儿童中CKD的疫苗接种覆盖率低于最佳.
- 对于儿科CKD免疫反应的理解有所进步,揭示了特定的脆弱性.
- 疫苗接种坚持的障碍是多因素的,其中一些是这个人群独有的.
结论:
- 提高患有CKD的儿童的疫苗接种率对于减轻感染风险至关重要.
- 建议在儿童慢性病患者的复杂护理框架内优先进行免疫接种.
- 针对性干预措施,根据成人CKD协议进行调整,有望提高疫苗接种率.
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