OAZ1 / CASP8AP2 双淘汰赛通过代谢重编程和抗亡作用增强了HEK293细胞中重组蛋白质的产生

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Updated: Jan 29, 2026

Author Spotlight: Advancing Gene Therapy with High-Yield AAV Vectors Through HEK293 Suspension Cell Cultivation
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Published on: April 26, 2024

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Junhe Zhang1,2,3, Liao Zhang1,2, Lu Hou1,2

  • 1Institutes of Health Central Plains, Xinxiang Key Laboratory for Tumor Drug Screening and Targeted Therapy, Henan Medical University, Xinxiang 453003, China.

Acta biochimica et biophysica Sinica
|January 28, 2026
PubMed
概括

我们通过敲除OAZ1和CASP8AP2基因,增强了HEK293细胞中的重组蛋白质生产,减少了细胞亡,并优化了新陈代谢以获得更高的产量.

关键词:
这就是CRISPR/Cas9的作用.在HEK293细胞中.重组蛋白质蛋白质的重组蛋白质是什么?

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