Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Resistivity01:22

Resistivity

4.5K
When a voltage is applied to a conductor, an electrical field is generated, and charges in the conductor feel the force due to the electrical field. The current density that results depends on the electrical field and the properties of the material. In some materials, including metals at a given temperature, the current density is approximately proportional to the electrical field. In these cases, the current density can be modeled as:
4.5K
Resistance01:19

Resistance

5.9K
When a current moves through any conductor, the conductor causes some level of difficulty for the current to flow. The measure of that difficulty is known as the resistance of the material and is represented by R. Every material has its own resistance. In the case of conductors, heat is emitted whenever a current passes through them. Resistance depends on the resistivity of the material. Resistivity is a characteristic of the material used to fabricate electrical components, whereas the...
5.9K
Equivalent Resistance01:16

Equivalent Resistance

976
In circuit analysis, situations often arise where resistors are neither in series nor parallel configurations. To tackle such scenarios, three-terminal equivalent networks like the wye (Y) (Figure 1 (a)) or tee (T) and delta (Δ) (Figure 1 (b)) or pi (π) networks come into play. These networks offer versatile solutions and are frequently encountered in various applications, including three-phase electrical systems, electrical filters, and matching networks.
976
Resistance and Conductance01:25

Resistance and Conductance

509
A conductor's DC resistance at a given temperature is influenced by its resistivity, length, and cross-sectional area. Resistivity is an inherent property of the conductor material, with annealed copper serving as the international standard for measurement. For instance, the resistivity of hard-drawn aluminum at 20 degrees Celsius is 61% of the standard conductivity of annealed copper.
Various factors impact the resistance of a conductor. Spiraling in stranded conductors increases their...
509
Rolling Resistance01:21

Rolling Resistance

640
When a solid cylinder rolls steadily on a rigid surface, the normal force applied by the surface on the cylinder is perpendicular to the tangent at the contact point. However, since no materials are entirely rigid, the surface's reaction to the cylinder involves a range of normal pressures.
For instance, imagine a hard cylinder rolling on a comparatively soft surface. The cylinder's weight compresses the surface beneath it. As the cylinder moves, the material in front of it slows down due to...
640
Vascular Resistance01:20

Vascular Resistance

10.7K
Vascular resistance is a critical concept in understanding blood flow dynamics in the circulatory system. It refers to the resistance that blood encounters as it flows through the blood vessels. This resistance is a key factor in determining blood pressure and cardiac workload.
The primary determinants of vascular resistance are vessel diameter, blood viscosity, and vessel length. Among these, vessel diameter plays the most significant role due to the fourth power relationship described by...
10.7K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

ASSOCIATION BETWEEN MACROCYCLIC LACTONE AND BENZIMIDAZOLE RESISTANCE IN THE DOG HOOKWORM ANCYLOSTOMA CANINUM.

The Journal of parasitology·2026
Same author

HOOKSNIP: A BROWSER TOOL FOR DESIGNING ALLELE-SPECIFIC PCR PRIMERS IN HOOKWORM.

The Journal of parasitology·2026
Same author

Ultrafiltration as an alternative purification method for bovine serum albumin-fluorescein isothiocyanate bioconjugate.

microPublication biology·2025
Same author

Differential Emodepside Efficacy in Drug-Resistant and Drug-Susceptible <i>Ancylostoma caninum</i> Highlights Variability in Potassium Channel Activity.

Tropical medicine and infectious disease·2025
Same author

Sex-Specific Immune Responses Mediate Host Specificity in Hookworm Infections.

Tropical medicine and infectious disease·2025
Same author

Challenges in establishing small animal models for <i>Ancylostoma caninum</i> : Host specificity and resistance to infection in rodent hosts.

microPublication biology·2025

相关实验视频

Updated: Jan 29, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
05:10

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

10.2K

药物重新定位用于对抗多药耐药虫.

Elise L McKean1, Catherine A Jackson2, Abigail Dowd1

  • 1Department of Biological Sciences, The George Washington University, DC, USA.

Biology open
|January 28, 2026
PubMed
概括

虫耐药性是一个日益严重的问题. 机器学习发现前列腺癌药物胺对抗耐药虫有效,提供了一种新的治疗途径.

关键词:
安基洛斯托马 (ancylostoma caninum) 是一种类动物.抗虫耐药性 抗动物耐药性药物重新定位是药物重新定位.虫是一种虫.机器学习 机器学习

更多相关视频

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.6K
In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
09:29

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging

Published on: April 28, 2017

9.9K

相关实验视频

Last Updated: Jan 29, 2026

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
05:10

Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

Published on: December 11, 2016

10.2K
The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis
23:06

The MODS method for diagnosis of tuberculosis and multidrug resistant tuberculosis

Published on: August 11, 2008

19.6K
In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging
09:29

In Vivo Investigation of Antimicrobial Blue Light Therapy for Multidrug-resistant Acinetobacter baumannii Burn Infections Using Bioluminescence Imaging

Published on: April 28, 2017

9.9K

科学领域:

  • 寄生虫学的寄生虫学
  • 药物发现 药物发现 药物发现
  • 计算生物学 计算生物学

背景情况:

  • 抗虫耐药性 (AR) 威胁着土壤传播的虫控制,特别是在依赖于本齐米达的大规模药物管理 (MDA) 的情况下.
  • 迫切需要新的治疗方法来对抗多种甲虫耐药 (MADR) 甲虫.

研究的目的:

  • 开发一种机器学习 (ML) 引导的药物重定向管道,以识别有效对抗Ancylostoma caninum的MADR分离物的化合物.
  • 为了加快对AR的新治疗方法的发现.

主要方法:

  • 训练有素的ML分类器在精心策划的甲虫数据集上.
  • 使用ML管道从DrugBank选批准的药物.
  • 通过卵试验 (EHA),幼虫发育试验 (LDA) 和成人生存试验验证实了选择的化合物.

主要成果:

  • 非类固醇抗雄激素Flutamide对MADR虫表现出强烈的活性.
  • 胺对卵和幼虫阶段表现出特定的活性,抑制卵化和阻止幼虫发育.
  • 该药物表现出度依赖的效应.

结论:

  • 药物重新定位是发现针对MADR虫的治疗方法的一个有价值的策略.
  • 富lutamide显示承诺作为对抗药性虫感染的潜在治疗方法.
  • 这项研究强调了计算方法在应对关键公共卫生挑战方面的翻译潜力.