在数字辅助手术中切除下骨髓母细胞瘤的安全手术幅度较小
Zi-Li Yu1,2, Lei Chen1, Chun-Bo Dou3
1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, China.
International journal of surgery (London, England)
|January 28, 2026
概括
数字手术指南提供了精确切割下骨髓母细胞瘤. 6毫米的骨边缘是实际的最低限度,尽管对于激进的瘤切除仍然存在4%的积极边缘风险.
科学领域:
- 口腔和牙面部外科手术
- 在瘤学瘤学.
- 数字手术规划数字手术规划
背景情况:
- 数字化手术指南的临床采用,以切除乳腺母细胞瘤是有限的.
- 确定完全切除瘤的安全外科边缘需要进一步的研究.
研究的目的:
- 评估下骨髓母细胞瘤切除过程中数字手术指南的精度.
- 根据组织病理学来确定激进瘤切除的最低安全骨边缘距离.
主要方法:
- 分析了23名接受数字引导细分下切除术的患者.
- 利用3D虚拟手术规划来定义骨切除边缘.
- 对比计划与实际的边际,并评估了两组具有不同目标边际大小 (5-10mm和6mm) 的队列中的本病理边际状态.
主要成果:
- 数字指导显示出毫米级的精度,计划和实际边际之间的平均偏差为1.05毫米 (队列1).
- 在第1组中,所有边际在组织病理学上都是负的.
- 在第2组中观察到4.0%的阳性边缘率,计划边缘为6毫米,前边缘为常规乳腺母细胞瘤阳性.
结论:
- 数字手术指导提供了高精度下骨髓母细胞瘤切除.
- 6毫米的骨边缘可能是平衡瘤安全和功能的实际最低限度.
- 即使在6毫米的规划距离下,也存在4.0%的正利率风险,需要仔细考虑.
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