识别被β-catenin抑制或独立于β-catenin的Wnt调节基因

Shiyang Liu1,2, Sara Haghani3, Enrico Petretto2,4

  • 1Program in Cancer and Stem Cell Biology, Duke-NUS School of Medicine, Singapore.

The FEBS journal
|January 28, 2026
PubMed
概括

Wnt信号控制基因表达通过β-catenin,但也独立地. 这项研究揭示了10%的Wnt调节基因是β-catenin独立的,经常被抑制,并确定了参与Wnt抑制的负调节元件 (NRE).

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