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怀孕前和怀孕期间根据COVID-19感染状况的不良怀孕和婴儿结果
Kelly J Hunt1,2, Chun-Che Wen1, Kalyan J Chundru1
1Department of Public Health Sciences Medical University of South Carolina Charleston South Carolina USA.
怀孕前和怀孕期间的COVID-19感染与母亲和婴儿不良结果的风险增加有关. 这包括高血压疾病,孕前,胎盘断裂和严重的孕产妇发病率,强调了疫苗接种和预防的重要性.
科学领域:
- 产科和妇科 产科和妇科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 之前的研究探索了怀孕期间的COVID-19风险.
- 这项研究独特地调查了与怀孕前的COVID-19感染相关的风险.
研究的目的:
- 分析妊娠前和妊娠期间COVID-19感染与妊娠和婴儿不良结果之间的关系.
- 评估诸如妊娠高血压障碍,孕产前,胎盘断裂,剖腹产,产后出血和严重孕产妇发病率等疾病的风险.
主要方法:
- 在南卡罗来纳州 (2020-2022) 对单子活产和胎儿死亡的回顾性队列研究.
- 链接出生证明,COVID-19诊断,医院出院,急诊室和医疗补助资格数据.
- 使用日志双项和修改的Poisson模型来估计风险比率,调整社会人口统计学,临床和行为因素.
主要成果:
- 怀孕前COVID-19感染增加了怀孕高血压疾病 (HDP),孕前/孕和剖腹产的风险.
- 在第一/第二季度感染增加了孕前/孕,胎盘断裂和严重孕产妇发病率 (SMM) 的风险.
- 第三个三个月的感染增加了孕前/孕,胎盘断裂,产后出血和SMM的风险.
结论:
- 怀孕前和怀孕期间的COVID-19感染与不良妊娠结果有显著的关联.
- 怀孕前的COVID-19感染显示出与HDP,孕前/孕和剖腹产的显著关联.
- 孕期COVID-19感染,特别是在第三个三个月,增加了胎盘断裂,产后出血和SMM的风险.
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