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Updated: Jan 29, 2026

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基于机器学习和深度学习的最新趋势,对G蛋白合受体-连接体结合 afinities 的预测

Joshua Stephenson1, Konda Reddy Karnati1

  • 1Department of Natural Sciences, Bowie State University, Bowie, MD, United States.

Frontiers in bioinformatics
|January 28, 2026
PubMed
概括

预测蛋白质 - 配体结合亲和力对于药物发现至关重要. 本综述将机器学习模型 (基于序列,图形和结构) 分类为预测结合亲和关系,特别是对于G蛋白结合受体 (GPCRs).

关键词:
G蛋白结合受体 (GPCRs) 是一种结合性亲缘关系预测预测深度学习 (DL) 是指深度学习.药物目标结合亲和力机器学习 (ML) 是指机器学习.

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