童年时的情感忽视调节了成年时左侧神经的无周期偏移
Sota Inoue1,2, Naofumi Otsuru2,3, Hitomi Ikarashi2,3
1Graduate School, Niigata University of Health and Welfare, Niigata, Japan.
Frontiers in neuroscience
|January 28, 2026
概括
早期的情感疏忽改变了成年人大脑的功能,特别是左侧的激发-抑制平衡. 这种神经生理变化可能会长期存在,影响大脑刺激能力.
科学领域:
- 神经科学是一个神经科学.
- 精神病学是一个精神病学.
- 脑部成像 脑部成像
背景情况:
- 早期生活压力 (ELS) 是成人疾病的重要风险因素.
- 神经活动的非周期性组成部分是大脑刺激-抑制 (E/I) 平衡的新标志物.
研究的目的:
- 通过非周期性神经活动研究ELS对成人大脑功能的影响.
- 检查生命早期情绪疏忽与大脑E/I平衡之间的关系.
主要方法:
- 在65名健康成年人中记录了静止状态磁脑电图 (MEG).
- 通过童年创伤问卷 (CTQ-JNIMH) 评估ELS.
- 使用FOOOF算法提取了无周期性神经活动.
主要成果:
- 40%的参与者报告了情绪上的忽视.
- 情绪疏忽与左侧神经元中非周期性偏移之间的显著负相关性.
- 在非周期性偏移和当前的抑郁或焦虑水平之间没有发现相关性.
结论:
- 早期的情感疏忽会导致持续的脑部变化.
- 周期性偏移变化可能反映出左侧轨道神经元 (pars orbitalis) 激发能力增加的转变.
- 无周期性神经活动是ELS相关大脑变化的潜在生物标志物.
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