一个24周的多组分炼计划改善了轻度认知障碍的老年人的认知和身体组成:一项随机对照试验
Danming Xu1, Xiaochu Wu2, Junming Dai1
1Strength and Conditioning Center, Chengdu Sport University, Chengdu, Sichuan, China.
Frontiers in aging neuroscience
|January 28, 2026
概括
24周的多组分运动干预改善了轻度认知障碍 (MCI) 的老年人身体组成. 然而,它在本研究中没有显示出显著的认知改善.
科学领域:
- 老年学和运动科学
- 神经学和认知健康
背景情况:
- 轻度认知障碍 (MCI) 影响老年人,影响身体组成和认知功能.
- 基于社区的干预措施对于管理与年龄有关的健康状况至关重要.
研究的目的:
- 研究为期24周的社区多组分运动干预 (MCEI) 对患有MCI的老年人身体组成和认知功能的影响.
- 为了评估骨肌肉质量,脂肪质量和认知测试成绩的变化.
主要方法:
- 一个单中心,并行组随机对照试验 (RCT) 涉及64名65-75岁的MCI成年人.
- 参与者被分配到MCEI (有氧,抵抗,平衡训练) 或通常活动控制组.
- 主要结局包括骨肌肉质量 (SMM),脂肪质量指数 (FMI),迷你精神状态检查 (MMSE) 和蒙特利尔认知评估 (MoCA).
主要成果:
- 与对照组相比,在MCEI组中观察到SMM的显著改善和FMI的减少.
- 对于骨肌肉指数 (SMI),MMSE,MoCA或动物流利性测试 (AFT) 没有发现显著的相互作用效应.
结论:
- 在患有MCI的老年人中,24周的MCEI计划有效地改善了身体成分 (增加SMM,减少FMI).
- 干预措施没有在查级认知措施中产生可测量的改善.
- 需要进一步研究更长的持续时间和认知挑战,以澄清运动-认知相互作用.
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