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Updated: Jan 29, 2026

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction
10:18

Author Spotlight: Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction

Published on: July 7, 2023

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针对αvβ3和PD-L1的双重功能抗体为固体瘤治疗提供了一个有前途的战略

Guixia Li1, Wenlei Li2, Liuli Wang1

  • 1Pharmacology and Toxicology Research Department, Tasly Research Center, Tasly Pharmaceutical Group Co., Ltd., Tianjin, China.

Frontiers in immunology
|January 28, 2026
PubMed
概括

一种新型的双重功能抗体B1451针对PD-L1和整蛋白αvβ3,在逆转癌症免疫逃避方面显示出希望. 这种抗体在临床前模型中表现出比单一治疗更高的抗瘤活性.

关键词:
在PD-L1中.抗体是一种抗体.固体瘤是一个固体瘤.瘤免疫学 瘤免疫学其他 其他 其他

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