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Updated: Jan 29, 2026

Using RNA-interference to Investigate the Innate Immune Response in Mouse Macrophages
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脊椎动物中LPS诱导的转录变化的目录识别了合成保存的人类长非编码RNAs,这些RNA调节了先天免疫反应

Marina R Hadjicharalambous1, Richard R Ryder1, Peter S Fenwick2

  • 1Department of Life Science, University of Bath, Bath, United Kingdom.

Frontiers in immunology
|January 28, 2026
PubMed
概括

这项研究确定了参与脊椎动物天生的免疫反应的合成保存的长非编码RNA (lncRNAs). 这些保存的lncRNAs,如MITA1 (IL7AS) 和LINC02541,在调节对LPS的炎症反应中发挥作用.

关键词:
在LPS中使用LPS.进化 演化 演化 演化 演化 演化 演化 演化具有天生的免疫力.长长的非编码RNAs.转录组学 转录组学是指转录组学.脊椎动物 脊椎动物

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