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中国西南地区百日咳的流行病学和时空集群特征,2013-2024年
Ju Wang1,2, Jiawei Xu1,2, Dayong Xiao1,2
1Department of Infectious Disease Prevention and Control, Chongqing Municipal Center for Disease Control and Prevention (Chongqing Academy of Preventive Medicine), Chongqing, China.
Frontiers in public health
|January 28, 2026
概括
百日咳 (百日咳) 在中国急剧增加,在2024年病例急剧增加,特别是在学龄儿童中. 这种复苏凸显了需要更新的监测和控制策略来管理百日咳流行病学.
科学领域:
- 流行病学 流行病学
- 传染病监测 传染病监测 传染病
- 公共卫生 公共卫生
背景情况:
- 尽管儿童疫苗接种率很高,但中国的百日咳 (百日咳) 病例正在复苏.
- 了解百日咳不断变化的流行病学对于有效的公共卫生干预至关重要.
- 本研究侧重于2013年至2024年中国重庆市咳报告率的时空趋势和关键驱动因素.
研究的目的:
- 分析中国重庆市 (2013-2024) 百日咳报告率的时空趋势.
- 确定影响百日咳报告率的关键驱动因素,包括诊断标准修订和社会经济因素.
- 描述研究期间咳病例年龄分布的变化.
主要方法:
- 来自国家可通报传染病报告系统 (NNDRS) 的纵向监测数据的分析.
- 结点回归用于趋势分析,中断时间序列分析用于诊断标准影响,以及时空扫描统计数据用于集群识别.
- 利用多层线性混合效应模型来评估与通知率相关的地区级因素.
主要成果:
- 观察到咳病例大幅增加,在2024年发生68.55%的咳病例.
- 发现了年龄分布的流行病学转变:虽然1岁以下的婴儿报告率最高,但5-10岁的儿童在2024年成为最大的病例群体.
- 2024年对国家诊断标准的修订与通知增加了26.5倍;较高的地区收入水平也与增长率有关.
结论:
- 重庆出现了大量 pertussis 的复苏,标志着对学龄儿童的转变成为2024年占主导地位的病例群体.
- 诊断标准的修订对通知率产生了重大影响,强调需要仔细解释监测数据.
- 建议建立血清流行病学监测,以量化人口免疫力,并为咳的有针对性的控制策略提供信息.
关键词:
pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis pertussis复苏的复苏是一个复苏.时间空间分析.疫苗 疫苗 疫苗 疫苗百日咳 百日咳是什么意思
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