口服的Streptococcus mutans在高虫风险婴儿中的水平婴儿的虫风险很高
Bella Weijia Luo1, Ka Fung Yu1, Pei Liu1
1Faculty of Dentistry, The University of Hong Kong, Pokulam, Hong Kong SAR, China.
Frontiers in dental medicine
|January 28, 2026
概括
这项研究发现,婴儿的唾液和斑块中含有低水平的*Streptococcus mutans* (MS). 斑块中较高的MS水平,而不是唾液,与高风险婴儿的早期牙损伤有关.
科学领域:
- 儿科牙科 儿科牙科
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 幼儿 (ECC) 是一个重要的公共卫生问题.
- 婴儿口腔微生物组,特别是Streptococcus mutans (MS),在脏病的发展中起着至关重要的作用.
- 识别高危婴儿对于有针对性的预防策略至关重要.
研究的目的:
- 量化高风险婴儿的唾液和斑块中的*Streptococcus mutans* (MS) 水平.
- 探索MS水平与牙的早期症状之间的关联.
- 确定与婴儿多发性硬化症水平升高相关的危险因素.
主要方法:
- 通过家长问卷招募了579名1岁婴儿,这些婴儿被确定为患有虫的高风险.
- 采集的唾液和斑块样本用于MS量化使用实时PCR.
- 进行了临床检查,以评估病经验和口腔卫生.
- 分析了人口和行为数据,包括饮食习惯和家庭规模.
主要成果:
- 唾液和斑块中MS的平均数量很低,很少有婴儿表现出高的MS百分比.
- 斑块中较高的MS水平,但不是唾液,与白斑病变或洞穴病变 (P=0.039) 有显著的关联.
- 来自较大家庭的婴儿 (≥2个孩子) 和每天食≥7次的婴儿患上斑块MS的可能性更高 (分别P=0.029和P=0.020).
结论:
- 在婴儿的唾液和斑块中,MS的总体水平通常很低.
- 与唾液性MS相比,斑块性MS水平与幼儿早期牙损伤发病的相关性更强.
- 家庭规模和频繁的养是增加婴儿牙斑中多发性硬化菌的潜在危险因素.
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