通过皮肤进行的耳膜迷走神经刺激对接受激进乳房切除术的患者的外科手术期间焦虑的影响:随机对照临床试验的研究方案
Jiayi Tang1, Ming Yao1, Tong Wu1
1Department of Anesthesiology and Pain Research Center, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, China.
Frontiers in neurology
|January 28, 2026
概括
通过皮肤进行耳道迷走神经刺激 (taVNS) 可以减少乳腺癌患者接受乳房切除术的焦虑. 这项研究调查了taVNS用于管理手术前焦虑,可能改善手术结果和恢复.
科学领域:
- 医疗干预 医疗干预
- 神经调节是一种神经调节.
- 在瘤学瘤学.
背景情况:
- 乳腺癌手术,特别是乳房切除术,经常会引起患者的严重焦虑.
- 这种焦虑会对手术结果和术后恢复产生负面影响.
- 对这些患者的术后焦虑有效干预措施的研究有限.
研究的目的:
- 为了研究通过皮肤进行耳道迷走神经刺激 (taVNS) 在接受激进乳房切除术的患者中减少术前焦虑的疗效.
- 探索taVNS作为一种新的临床策略,用于预防和管理这种患者群体的焦虑.
主要方法:
- 一项前性,双盲,随机对照试验,涉及202名符合条件的急性乳房切除术患者.
- 患者被随机分配,在麻醉前和术后三天接受taVNS或假刺激.
- 主要结局:外科手术期间焦虑缓解率. 二级结局:HAMA,PSQI,CAM-3D,NRS,FRAIL,以及心率变化 (HRV) 等.
主要成果:
- 数据分析正在等待;结果将比较taVNS和假组之间的焦虑缓解率和二次结果.
- 这项研究旨在提供关于taVNS治疗外科手术期间焦虑的疗效的可靠数据.
结论:
- 通过调节自主神经功能,taVNS显示了缓解外科手术前焦虑的潜力.
- 这种干预可以提供一种创新的方法,以改善乳房切除术后的患者结果和生活质量.
- 进一步的研究和taVNS的临床应用是有必要的.
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