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Updated: Jan 29, 2026

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作为抗癌剂的小分子ATR激酶抑制剂的近期进展

Gurpreet Singh1, Ram Sharma2, Vinod Gautam3

  • 1Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, India.

Future medicinal chemistry
|January 28, 2026
PubMed
概括

ATAxia telangiectasia和Rad3相关 (ATR) 激酶抑制剂通过破坏DNA损伤反应途径在癌症治疗中显示出希望. 目前正在进行的研究重点是克服毒性和耐药性,以改善患者的治疗结果.

关键词:
在ATR激酶抑制剂中使用ATR激酶抑制剂.基因损伤反应 (DDR) 是一种对DNA损伤的反应.在PARP抑制剂组合中使用PARP抑制剂生物标志物指导治疗癌症治疗方法 癌症治疗方法复制压力是复制的压力.合成杀伤性 合成杀伤性

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