可穿戴侧流补丁用于非侵入性汗水蛋白监测
Yongxiang Ji1, Zhongzeng Zhou1, Benxing Su1
1College of Chemistry and Environmental Engineering, The Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong 518060, China.
ACS sensors
|January 28, 2026
概括
这项研究引入了一个可穿戴的汗液感应贴片,用于非侵入性,实时检测诸如C反应蛋白 (CRP) 等炎症蛋白生物标志物. 这项创新推进了用于汗水分析和潜在临床应用的可穿戴技术.
科学领域:
- 生物医学工程 生物医学工程
- 可穿戴技术可穿戴技术
- 生物感应是一种生物感应.
背景情况:
- 传统的蛋白质分析需要侵入性方法,限制了现场监测.
- 现有的可穿戴传感器在稳定和敏感的汗水蛋白检测方面扎.
- 需要对汗水中的C反应蛋白 (CRP) 等炎症因素进行非侵入性监测.
研究的目的:
- 开发一种可穿戴的汗水感应贴片 (WSSP),用于非侵入性,实时检测汗水蛋白生物标志物.
- 将汗液诱导,微流体学和侧流免疫检测集成到一个可穿戴平台中.
- 为了使汗水中C反应蛋白 (CRP) 的敏感和特定检测.
主要方法:
- 开发了一种可穿戴的汗感应贴片 (WSSP),结合了自热汗感应,微流体和侧流免疫试验.
- 利用基于智能手机的色度检测和机器学习来解释信号.
- 验证了WSSP的性能,用于监测休息和运动期间的C-反应蛋白 (CRP) 水平.
主要成果:
- 在WSSP实现了非侵入性,实时,特定和敏感的检测C反应蛋白 (CRP) 在汗水.
- 该设备成功地监测了运动前后汗水CRP水平的动态变化.
- 机器学习算法准确地解释了用于CRP量化的色度信号.
结论:
- 可穿戴的侧流补丁代表了汗水蛋白检测的重大进步.
- 通过汗水分析,WSSP平台可在现场监测炎症反应.
- 这项技术为未来在可穿戴诊断领域的临床应用奠定了基础.
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