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Updated: Jan 29, 2026

Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors
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Rapid Screening of HIV Reverse Transcriptase and Integrase Inhibitors

Published on: April 9, 2014

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从艾滋病毒感染者的HIV-1整合酶编码区域内插入的第一个特征

Nhat Quang Tu1, Thomas Montrouge2, Gladys Mbemba1

  • 1Laboratoire de Biologie et Pharmacologie Appliquée (LBPA), Université Paris-Saclay, ENS-Paris-Saclay, CNRS UMR 8113, Gif-sur-Yvette 91190, France.

The Journal of antimicrobial chemotherapy
|January 28, 2026
PubMed
概括

在HIV-1整合酶的插入突变减少病毒复制,但不会导致对整合酶链转移抑制剂 (INSTIs) 的耐药性. 这些发现对于理解HIV-1的演变和治疗策略至关重要.

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