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选择最佳方法来评估高血压介导的器官损伤:个性化的方法
Eva Gerdts1, Athanase Benetos2,3, Rosa Maria Bruno4,5
1Department of Clinical Science, Faculty of Medicine, University of Bergen, Bergen, Norway.
European journal of preventive cardiology
|January 28, 2026
概括
高血压中介器官损伤 (HMOD) 的评估对于确定心血管风险至关重要. 建议对所有患者进行基本检查,并根据临床发现对选定个体进行高级诊断.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學專業.
- 高血压管理 高血压管理
背景情况:
- 高血压介导器官损伤 (HMOD) 的易感性因遗传学,年龄,性别和并发症而异.
- 指导方针普遍建议HMOD评估用于识别高心血管风险.
- 在临床实践中优化HMOD诊断在选择适当的策略和工具方面存在挑战.
研究的目的:
- 在临床实践中提供专家建议,以优化高血压介导器官损伤 (HMOD) 的诊断.
- 综合主要心血管和高血压学会对HMOD评估的当前指导方针.
- 为管理高血压患者的临床医生提供实用方法.
主要方法:
- 对HMOD评估的建议进行了一次审查,该评估涉及了主要的国际高血压和心脏病学指南.
- 分析了欧洲心脏病学会 (2024年),欧洲高血压学会 (2023年),美国心脏协会/美国心脏病学会 (2025年) 和国际高血压学会 (2020年) 的指导方针.
- 根据综合的指导方针建议,制定了一份专家意见.
主要成果:
- 对于所有高血压患者,建议对心脏和脏HMOD进行基本评估,使用心电图,血清肌素,估计的淋巴细胞过率和尿液白蛋白-肌素比率.
- 根据初步的临床评估,对管理的潜在影响和资源的可用性,建议对HMOD进行高级诊断测试.
- 心声图是首选的先进初始测试,具有预后价值;对于特定的患者群体,可以考虑进一步的测试,如冠状动脉分数或脉冲波速度.
结论:
- 高血压介导器官损伤 (HMOD) 是心血管风险升高的重要标志物.
- 常规的基本HMOD评估对于所有被诊断为动脉高血压的患者至关重要.
- 对于需要进一步风险分层或管理调整的患者,建议选择性使用先进的诊断模式.
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