在皮肤外科手术患者的外科手术期间的脂质体布皮瓦卡因注射的安全性
Melissa M Rames1, Jorge A Rios-Duarte1, Nahid Y Vidal2
1Department of Dermatology, Mayo Clinic, Rochester, Minnesota.
概括
脂质体布皮瓦卡因 (LB) 是安全有效的皮肤外科手术后的疼痛缓解. 这项研究在接受LB的患者中没有发现局部麻醉系统毒性 (LAST) 的病例.
科学领域:
- 皮肤外科手术皮肤外科手术
- 麻醉学 麻醉学
- 药理学 药理学是指药理学的学科.
背景情况:
- 在皮肤外科手术中对脂质体布皮瓦卡因 (LB) 的使用存在有限的研究.
- 在这种环境中,了解LB的特性和安全概况至关重要.
研究的目的:
- 为了评估外科手术后腰部的治疗特征.
- 为了确定与LB使用相关的不良事件,包括局部麻醉系统毒性 (LAST).
主要方法:
- 对接受外科手术期间下巴治疗的患者的回顾性图表审查.
- 纳入标准:接受皮肤外科手术的18岁以上的患者.
主要成果:
- 在129名患者中分析了140次LB的管理.
- LB经常用于切除和莫斯手术,特别是在腺炎和皮肤瘤.
- 没有观察到局部麻醉系统毒性 (LAST);1.5%的人经历了轻微的恶心,可能与阿片类药物使用有关.
结论:
- 在皮肤外科手术中,脂质组布皮瓦卡因耐受性良好,有效治疗术后疼痛.
- 没有报告局部麻醉系统毒性 (LAST),支持其考虑用于疼痛管理.
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