考虑心血管疾病风险分层的精细体育活动建议:一个队列研究
Chenxi Yuan1,2,3, Tao Zhou1,2,4, Xiang Cui1,2
1Department of Epidemiology, Fuwai Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College/National Center for Cardiovascular Diseases, Beijing 100037, China.
European journal of preventive cardiology
|January 28, 2026
概括
个性化体育活动 (PA) 是预防心血管疾病 (CVD) 的关键. 根据个体心血管疾病风险量身定制运动强度和持续时间,最大限度地提高益处,最大限度地减少潜在危害.
科学领域:
- 预防心血管疾病预防心血管疾病
- 运动生理学 运动生理学
- 公共卫生 公共卫生
背景情况:
- 当前的体力活动 (PA) 建议往往是一般化的.
- 不同心血管疾病 (CVD) 风险群体的最佳PA模式尚未确定.
- 需要个性化PA策略来完善公共卫生指南.
研究的目的:
- 为了确定不同心血管疾病风险人群的优化PA模式.
- 根据个人风险,完善现有的PA建议.
- 为了调查PA和事件心血管疾病之间的关联,跨风险层.
主要方法:
- 对72,884名英国生物库参与者的前性队列研究.
- 分析了加速器衍生的PA指标 (TPA,MPA,VPA,MVP,静止时间).
- 使用SCORE2,SCORE2-老年人和SCORE2-糖尿病模型进行心血管疾病风险分层.
- 用于建模PA-CVD关联的考克斯回归和组成数据分析.
主要成果:
- 总PA (TPA) 和中度至强度PA (MVPA) 与发生心血管疾病之间的反向关联.
- 非常高风险人群显示,增加MVPA (20%的危险降低每150分钟/周) 的最大好处.
- 确定了最佳活力PA (VPA) 值:高风险人群<60分钟/周,非常高风险人群<42分钟/周.
结论:
- 应根据个人心血管疾病风险来个性化PA建议.
- 定制VPA对于高风险和非常高风险群体至关重要,以最大限度地提高收益.
- 将风险评估纳入PA指导方针可以提高心脏保护效果和安全性.
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