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Updated: Jan 29, 2026

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预期和针对性反对开放标签安慰剂效应的作用
1University of New South Wales, Sydney, NSW, Australia.
Journal of health psychology
|January 28, 2026
概括
开放标签安慰剂 (OLPs) 显著改善了幸福感,预期在治疗后的经验中发挥了作用. 在本研究中,量身定制的健康反并没有进一步增强OLP效应.
科学领域:
- 心理学 心理学 心理学
- 行为科学 行为科学
- 医学人文学科 医学人文学科
背景情况:
- 开放标签安慰剂 (OLP) 涉及不欺骗性给予惰性治疗.
- OLP 效应背后的机制,特别是期望和反的作用,需要进一步研究.
- 现有的研究显示了OLP效应及其介质的不一致性.
研究的目的:
- 探索期望和量身定制的健康反对OLP效应的影响.
- 调查预期如何调解与治疗经验相关的OLP结果.
- 调和有关OLP机制的文献中的不一致性.
主要方法:
- 一项预先注册的随机对照试验,共293名健康参与者.
- 有三个组:具有反的OLP (OLP-Feedback),没有反的OLP (OLP-标准) 和无处理控制 (NTC).
- 在线自动化程序,在基线,第5天和第10天评估福祉 (负面情绪,睡眠质量).
主要成果:
- 与NTC相比,OLP治疗显著改善了幸福感.
- 量身定制的健康反并没有显著增强OLP效应.
- 在OLP组中,改善的预期增加了,在治疗经验后,在个人层面中介结果.
结论:
- 开放标签的安慰剂可以有效地提高幸福感,而不依赖于特定的反.
- 预期是OLP效应的关键媒介,特别是在参与者获得治疗经验后.
- 这项研究为推动OLP效应的机制提供了更清晰的理解.
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