血液中的度和儿童的抑郁和焦虑症状
Christian Hoover1,2, George Papandonatos3, Kim M Cecil4,5,6
1Department of Epidemiology, Brown School of Public Health, Providence, Rhode Island.
JAMA network open
|January 28, 2026
概括
儿童暴露与以后的抑郁症状有关,特别是在儿童后期暴露. 这凸显了防止暴露和保护儿童心理健康的持续努力的必要性.
科学领域:
- 环境健康 环境健康
- 儿童心理学 儿童心理学
- 神经发育障碍 神经发育障碍
背景情况:
- 早期发育中低水平的暴露与认知缺陷和行为问题有关.
- 儿童中暴露与抑郁/焦虑之间的关联尚未得到充分研究,特别是在儿童晚年.
研究的目的:
- 为了研究血中低水平的连续度与儿童的抑郁/焦虑症状之间的关系.
- 确定潜在的易受暴露对心理健康影响的敏感期.
主要方法:
- 一项前性队列研究跟踪了218名儿童,从早期发育到12岁.
- 血水平在1,2,3,4,5,8岁和12岁的年龄段被连续测量.
- 抑郁和焦虑症状在12岁时使用BASC-3,CDI-II和SCARED进行评估.
主要成果:
- 儿童血液中平均度的每一次翻倍都与自我报告的抑郁症状 (BASC-3) 的风险增加有关.
- 血液中含量和抑郁症状之间的显著关联在8岁时出现.
- 通过CDI-II.II测量的焦虑症状或抑郁症没有发现显著的关联.
结论:
- 儿童中低水平的暴露与儿童后期的抑郁症状有关.
- 儿童后期和青春期早期的暴露显示出特别大的风险增加.
- 研究结果强调了预防暴露的重要性,以支持儿童的心理健康.
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