苏尔福拉作为甲基胺补充剂治疗注意力缺陷/多动障碍:一项随机,双盲,安慰剂控制的试验
Farnaz Ghannadi1, Ahmad Shamabadi1, Mohammad Saleh Talebinejad1
1Psychiatric Research Center, Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Clinical neuropharmacology
|January 28, 2026
概括
苏尔福拉,当添加到甲基酸盐,显著改善了儿童注意力缺陷/多动症 (ADHD) 症状. 这种组合疗法被发现是安全的,耐受性很好,为管理ADHD提供了一个有前途的新方法.
科学领域:
- 神经科学是一个神经科学.
- 药理学 药理学是指药理学的学科.
- 儿科 儿科 儿科
背景情况:
- 注意缺陷/多动障碍 (ADHD) 存在重大治疗挑战.
- 需要新的治疗策略来解决当前ADHD治疗的局限性.
- 苏尔福拉具有神经保护性,抗炎性和抗氧化性质,表明潜在的治疗益处.
研究的目的:
- 调查硫福拉作为儿童多动症辅助疗法的疗效和安全性.
- 评估硫福拉对ADHD症状的影响,包括注意力不集中和过度活跃-冲动性.
主要方法:
- 这是一项随机对照试验,涉及70名年龄在6-11岁的ADHD儿童.
- 参与者接受了甲基化物加上硫黄 (30毫克/天) 或安慰剂8周.
- 在基线,第4周和第8周,老师和家长使用ADHD评分表 (ADHD-RS) 评估了ADHD症状.
主要成果:
- 与安慰剂组相比,在硫福拉组中观察到ADHD-RS总,注意力缺失和过度活跃-冲动性得分的显著降低.
- 硫福拉辅助疗法获得了更高的治疗反应率,强大的改善和缓解.
- 副作用的发生频率在硫福拉和安慰剂组之间是可比的,这表明耐受性良好.
结论:
- 在甲基化物治疗中添加硫福拉,对患有ADHD的儿童有显著的益处.
- 组合疗法有效地改善了注意力不集中,过度活跃-冲动性和ADHD整体症状.
- 苏尔福拉被发现是对甲基酸的安全且耐受良好的补充剂,用于儿科ADHD治疗.
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