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Updated: Jan 30, 2026

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DOCK8和STAT3合作抑制IgE诱导的T毛囊辅助细胞

Emily R Siniscalco1,2, Courtney Fisher3, Meng-Ping Lu3

  • 1Department of Immunobiology, Yale University School of Medicine, New Haven, CT, USA.

The Journal of experimental medicine
|January 28, 2026
PubMed
概括

功能丧失的DOCK8和STAT3变体会导致IgE高综合征. 由于DOCK8缺乏导致食物过敏,它促进T卵泡辅助13 (Tfh13) 细胞,而STAT3则抑制它们.

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