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相关概念视频

Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

376
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
376
Peripheral Artery Disease IV: Nursing Management01:26

Peripheral Artery Disease IV: Nursing Management

375
 The nursing management of a patient with peripheral artery disease (PAD) begins with a thorough assessment of the patient’s health history and clinical manifestations.AssessmentHealth History: Evaluate the patient’s history of hypertension, hyperlipidemia, family history of cardiovascular issues, and lifestyle factors such as dietary patterns, smoking, and physical activity.Physical Examination:Assess the affected extremity for decreased or absent peripheral pulses,...
375
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

332
Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
332
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

414
During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
414
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

424
Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
424
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

1.1K
Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
1.1K

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相关实验视频

Updated: Jan 30, 2026

Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease
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Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease

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腿部周围动脉疾病 腿部周围动脉疾病

Mary M McDermott1,2

  • 1Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago.

The New England journal of medicine
|January 28, 2026
PubMed
概括

周围动脉疾病 (PAD) 影响全球数以百万计的人,严重损害了行走能力,特别是在严重的情况下. 治疗包括药物治疗,炼和对持续症状进行再血管化,以改善心血管健康和运动能力.

科学领域:

  • 心血管医学 心血管医学
  • 血管外科 血管外科
  • 老年病的医生 老年病的医生

背景情况:

  • 周围动脉疾病 (PAD) 影响全球超过2.36亿人.
  • 诊断的证实是脚-手臂指数低于0.90.
  • PAD的严重程度与在没有休息的情况下完成6分钟步行测试的能力降低相关,特别是在老年人中.

研究的目的:

  • 总结目前关于预防PAD患者心血管事件的建议.
  • 审查改善PAD患者步行能力的干预措施.
  • 概述在PAD管理中考虑腿部再血管化的标准.

主要方法:

  • 关于PAD流行病学,诊断和治疗指南的文献综述.
  • 对PAD的运动干预 (监督和家庭干预) 的研究分析.
  • 对PAD的药理和程序治疗选择的评估.

主要成果:

  • 强化治疗他类药物,抗血小板药物或阿司匹林与里瓦罗克萨班,血压控制 (<130/80毫米升),血黄和SGLT2抑制剂 (对于糖尿病患者) 建议用于预防心血管事件.
  • 监督和在家进行的步行炼计划都明显改善了PAD患者的步行功能.
  • 对于严重的PAD症状,有指示进行腿部再血管化,这些症状对包括运动在内的保守管理没有反应.

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Author Spotlight: Assessing the Reliability of Doppler Ultrasound in Measuring Leg Blood Flow
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相关实验视频

Last Updated: Jan 30, 2026

Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease
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Intravital Microscopy of Monocyte Homing and Tumor-Related Angiogenesis in a Murine Model of Peripheral Arterial Disease

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结论:

  • 周围动脉疾病的综合管理涉及到一个多方面的方法,结合药物治疗,生活方式的修改和有针对性的干预措施.
  • 运动是PAD治疗的基石,增强功能能力和生活质量.
  • 重血管化应保留在耐火病例中,以优化患者的治疗结果和资源配置.