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Updated: Jan 30, 2026

Large Scale Zebrafish-Based In vivo Small Molecule Screen
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Published on: December 30, 2010

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基于结构的虚拟查识别了TREM2向的小分子,这些小分子增强了微质细胞化

Sungwoo Cho1, Baljit Kaur1, Kevin Lam2

  • 1Department of Radiology, Molecular Imaging Innovations Institute (MI3), Weill Cornell Medicine, New York, New York, USA.

ChemMedChem
|January 28, 2026
PubMed
概括

研究人员确定了EN020,这是一种在骨髓细胞2 (TREM2) 上表达的触发受体的小分子调节器. 这种化合物增强了微质细胞化,为阿尔茨海默病 (AD) 提供了新的治疗途径.

关键词:
阿尔茨海默氏症的疾病是阿尔茨海默氏症.在TREM2中,我们可以使用TREM2.生物物理验证验证发现药物的发现.虚拟选 虚拟选 虚拟选

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