通过样本来源对电细胞学和亲临快速现场评估的比较准确性:一个多校园分析分析
Agnes I Udoh1, Taylor Strange1, Cecilia G Clement1
1Department of Pathology, The University of Texas Medical Branch, Galveston, TX, United States of America.
Annals of diagnostic pathology
|January 28, 2026
概括
电细胞学 (TC) 的准确性与面对面的快速现场评估 (ROSE) 对于细针吸收 (FNA) 诊断的准确性相当. 性能因样本地点而异,突出显示在多校区实践中需要特定地点的质量保证.
科学领域:
- 细胞病理学 细胞病理学
- 医疗信息学 医疗信息学
- 诊断的准确性 诊断的准确性
背景情况:
- 精细针吸收 (FNA) 的快速现场评估 (ROSE) 提高了样品的充分性和诊断准确性.
- 远程细胞学 (TC) 是一种正在发展中的个人ROSE的替代方案,特别适用于分布式医疗保健系统.
- 在各种样本类型中,TC与实体ROSE的比较准确性需要进一步调查.
研究的目的:
- 为了比较远程细胞学 (TC) 和个人快速现场评估 (ROSE) 的诊断准确性,用于细针吸收 (FNA) 标本.
- 分析不同解剖部位的TC和亲身ROSE的表现.
- 评估TC在多校园细胞病理学环境中的可行性.
主要方法:
- 从2022年至2023年,在三个校区对1697名ROSE初步诊断的FNA进行回顾性审查.
- 与最终诊断相比,亲身ROSE解释 (n=1459) 和TC解释 (n=238) 的比较.
- 分析主要差异 (良性至恶性或恶性至良性) 和统计测试 (基平方) 根据样本来源.
主要成果:
- 总体而言,主要差异率为个人ROSE的3%,TC的5%,没有统计学上显著的差异 (p=0.2429).
- 对于内脏部位 (肝脏,脏,胰腺胆道,肠道部位),TC显示数字上更高的一致性,而对淋巴结,头部/部和骨/软组织的亲身体验ROSE更准确.
- 电细胞学表明,整体准确性与人体ROSE相美,但性能因样本来源而异.
结论:
- 电脑细胞学是多个校园设置中面对面的ROSE的一个可行的替代方案,提供可比的诊断准确性.
- 标本来源是影响TC和亲身体验ROSE的表现的关键因素.
- 持续的质量保证和样本特定的评估对于TC在细胞病理学实践中的成功实施至关重要.
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