抑制T细胞激活的V域免疫球蛋白抑制剂通过PI3K/AKT信号通路调节CD4+ T细胞激活和Podocyte功能

Zhijie Luo1, Qiqi Zhang1, Tingting Zhang1

  • 1New Drug Screening and Pharmacodynamics Evaluation Center, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 210009, China.

概括

维域免疫球蛋白抑制T细胞激活 (VISTA) 调节狼性炎中的CD4+T细胞和细胞. 维斯塔激活通过调节免疫反应和保护细胞,为狼性炎提供了潜在的治疗点.

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