使用CPP/氨酸修饰的半孔化纳米颗粒口服输送利拉格卢提德:一种病毒启发的肠道吸收策略

Narges Shams1, Mehdi Esfandyari-Manesh2, Mohammad Sharifzadeh3

  • 1Department of Pharmaceutics, Faculty of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran.

Biomaterials advances
|January 28, 2026
PubMed
概括

一种新型模仿病毒的纳米载体通过克服胃肠道障碍来增强口服类药物输送. 这种空洞的中孔氧化纳米粒子系统改善了糖尿病老鼠的利拉格卢提德吸收和疗效,为注射提供了一个有前途的非侵入性替代品.

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