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相关概念视频

Parkinson's Disease: Overview01:15

Parkinson's Disease: Overview

Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is to...
Parkinson's Disease: Treatment01:24

Parkinson's Disease: Treatment

Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of its...
Parkinson Disease l: Introduction01:24

Parkinson Disease l: Introduction

Parkinson’s disease is a chronic, progressive neurodegenerative disorder that primarily affects movement. It is characterized by motor symptoms such as resting tremors, muscle rigidity, bradykinesia (slowness of movement), and postural instability. Patients may notice hand tremors at rest, stiffness during movement, or a shuffling gait. In addition to motor features, non-motor symptoms include sleep disturbances, mood and behavioral changes, constipation, and cognitive impairment, all of which...
Parkinson Disease ll: Pathophysiology01:24

Parkinson Disease ll: Pathophysiology

Parkinson disease (PD) is a progressive neurodegenerative disorder primarily affecting movement, with additional non-motor features. Its pathophysiology involves complex interactions among genetic susceptibility, environmental exposures, and cellular dysfunction, including dopaminergic neuron loss, protein aggregation, and mitochondrial impairment.Selective NeurodegenerationA key feature is the degeneration of dopaminergic neurons in the substantia nigra pars compacta, leading to reduced...

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相关实验视频

Updated: Jul 8, 2026

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
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Published on: October 13, 2016

眼运动功能测试参数与帕金森病之间的关联

Lei Zhang1, Hong Yao2, Xuelin Liang1

  • 1Department of Neurology, Jinshan District Central Hospital affiliated to Shanghai University of Medicine & Health Sciences, Shanghai 201599, China.

Clinical neurology and neurosurgery
|January 28, 2026
PubMed
概括
此摘要是机器生成的。

视频眼镜 (VOG) 显示了帕金森病 (PD) 患者显著的眼运动异常. 平方波冲击,追逐增益和冲击延迟的综合指数提高了PD查的准确性.

关键词:
帕金森病是帕金森氏症的一种疾病.萨卡德萨卡德 (Saccadé Saccade) 是一个古老的城市.顺利的追求顺利的追求.方形波蛋们,他们都是正方形波蛋.视门眼运动功能.视频眼镜摄影是一种视频眼镜.

更多相关视频

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
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Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
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Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

相关实验视频

Last Updated: Jul 8, 2026

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis
07:00

Eye-Tracking Control to Assess Cognitive Functions in Patients with Amyotrophic Lateral Sclerosis

Published on: October 13, 2016

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
10:28

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking
07:26

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

科学领域:

  • 眼科和神经病学 眼科和神经病学
  • 神经科学是一个神经科学.
  • 生物医学工程 生物医学工程

背景情况:

  • 帕金森病 (PD) 呈现出运动和非运动症状,包括眼运动功能障碍.
  • 眼运动异常是PD患者中公认的特征.
  • 了解这些功能障碍有助于诊断和管理.

研究的目的:

  • 用视频眼镜 (VOG) 来评估PD患者的眼运动功能.
  • 为了确定特定的生理参数和PD之间的关联.
  • 评估VOG在PD检测中的诊断潜力.

主要方法:

  • 招募了45名PD患者和45名健康对照.
  • 使用视频眼镜 (VOG) 来量化眼睛运动参数 (速度,延迟,增益,精度).
  • 评估了方波冲动 (SWJ) 和异常跟踪模式;采用了后勤回归和ROC分析.

主要成果:

  • 患有PD的患者表现出较高的SWJ率,较低的追逐收益,延长的冲击延迟时间和较慢的冲击速度.
  • SWJs,追求效率下降和延长的萨卡德延迟与PD有很强的关联.
  • 综合指数达到77.8%的灵敏度和82.2%的特异性 (AUC=0.836).

结论:

  • VOG评估揭示了PD中明显的眼运动异常,影响了固定稳定性,平滑的追逐和顺序控制.
  • 结合SWJs,追逐增益和saccade延迟的综合指数可以提高PD查精度.
  • VOG是检测和潜在查帕金森病的一个有价值的工具.