目标身体活动和死亡率在美国心脏协会的生活必需品中的关联 8 8
Anthony Mufarreh1, Kushagra Vashist2, Jacob Germany3
1Division of Cardiology, Department of Medicine, SUNY Upstate Medical University, Syracuse, New York, USA.
JACC. Advances
|January 28, 2026
概括
目标体育活动 (PA) 和美国心脏协会 (AHA) 生命必需品8 (LE8) 评分与降低死亡率有关. 然而,当考虑行为和代谢健康因素时,客观的PA与死亡率的关联性会减少.
科学领域:
- 心血管健康研究 心血管健康研究
- 死亡率研究 死亡率研究
- 公共卫生干预 公共卫生干预
背景情况:
- 美国心脏协会 (AHA) 的生命必需8 (LE8) 框架确定了包括体力活动 (PA) 在内的关键心血管健康指标.
- 之前的研究往往依赖于自我报告的PA数据,这容易导致不准确.
- 对PA的客观测量对于精确了解其对健康的影响至关重要.
研究的目的:
- 评估加速仪测量PA和AHALE8得分与所有原因和特定原因死亡率之间的关联.
- 为了比较客观的PA测量的预测值与传统的自我报告方法.
- 调查行为和代谢因素在PA死亡率关系中的作用.
主要方法:
- 使用手腕加速度计利用国家健康和营养检查调查 (2011-2012) 的数据.
- 根据实现的里程碑计算了AHA LE8分数.
- 使用后勤回归和曲线下面积 (AUC) 分析来评估PA和LE8与死亡率的关联,以混因素进行调整.
主要成果:
- 较高的加速度计测量PA类别显示了与较低的全因死亡率的初始关联,在调整行为和代谢因素后失去了意义.
- 较高的AHA LE8得分始终与全因死亡率的降低有关.
- 客观的PA测量表明,对所有死因的死亡率 (AUC:0.746) 有适度的歧视力,但对特定死因的死亡率没有.
结论:
- 增加的AHA LE8得分,包括客观的PA,与死亡风险降低相关.
- 当考虑行为和代谢健康因素时,单独的目标PA与全因死亡率没有显著的关联.
- 将客观的PA测量整合到诸如AHA LE8之类的心血管健康评估中,可以提供有价值的预后信息.
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