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Updated: Jan 30, 2026

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在严重的病毒性疾病中,人类对I型干扰素的自身抗体

Kevin Groen1, Benjamin G Hale1

  • 1Institute of Medical Virology, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.

Current opinion in virology
|January 28, 2026
PubMed
概括

中和I型干扰素的自身抗体 (IFN-Is) 模仿免疫缺陷,增加对严重感染的易感性. 这些自身抗体持续数十年,影响了对像SARS-CoV-2这样的病毒的防御,并带来了活衰减疫苗的风险.

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