在前列腺切除术后的勃起功能障碍男性中,使用内注射成功勃起功能的预测因素
Yotam Veredgorn1, Ziv Savin2, Ron Marom1
1Department of Urology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
概括
内注射 (ICI) 有效地治疗对PDE5抑制剂耐药的男性的根性前列腺切除术后的勃起功能障碍. 持续性尿失禁预测ICI治疗的反应较差.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 安德罗学与人类学
- 性医学性医学性医学性医学
背景情况:
- 内腔鼻内注射 (ICI) 是激进前列腺切除术 (RP) 后勃起功能障碍 (ED) 的常见治疗方法.
- 成功的ICI治疗结果的预测因素仍然不完全理解.
- 本研究研究了影响ICI后RP勃起功能恢复的临床和病理因素.
研究的目的:
- 在激进前列腺切除术 (RP) 后的男性中使用洞内注射 (ICI) 识别成功勃起功能的预测因素.
- 探索患者参数和通过ICI治疗实现的令人满意的勃起之间的关系.
主要方法:
- 对 ED post-RP 的男性进行前性研究,对 PDE5 抑制剂 (PDE5I) 无反应.
- 使用了TRIMIX的升级剂量 (papaverine,phentolamine,alprostadil).使用了增加剂量的TRIMIX.
- 使用勃起硬度度量表 (EHS) 和国际商失禁问卷-简短表格 (ICIQ-SF) 评估勃起功能.
主要成果:
- 85%的患者 (29/34) 通过ICI获得了令人满意的勃起功能.
- ICIQ-SF得分与勃起反应有显著的相关性 (p=0.001).
- 较高的ICIQ-SF得分与部分或无反应相关 (OR1.3,p=0.002).
结论:
- 内腔鼻内注射 (ICI) 是治疗勃起功能障碍的有效方法,在RP后的男性中,这些男性对PDE5抑制剂有抗性.
- 持续性尿失禁是ICI治疗次优反应的重要预测因素.
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