肠道微生物调节Helicoverpa armigera的免疫力,并影响其对微生物病原体的敏感性
Motahareh Amiri Domari1, Abbas Khani1, Najmeh Sahebzadeh1
1Department of Plant Protection, Faculty of Agriculture, University of Zabol, Zabol, Iran.
Journal of invertebrate pathology
|January 28, 2026
概括
削弱Helicoverpa armigera幼虫的肠道微生物群,削弱了它们的免疫反应,增加了对病原体的敏感性. 微生物组操纵可以增强对昆虫害虫的生物控制策略.
科学领域:
- 昆虫免疫学 昆虫免疫学
- 微生物组研究的研究.
- 害虫管理 害虫管理 害虫管理
背景情况:
- 与宿主相关的微生物群极大地影响昆虫的免疫力和抗病能力.
- 肠道微生物与类害虫的先天免疫之间的相互作用尚未完全理解.
研究的目的:
- 研究肠道微生物组操纵如何影响Helicoverpa armigera幼虫的免疫反应和病原体易感性.
- 探索微生物组操纵对生物害虫控制的潜力.
主要方法:
- 抗生素治疗以耗尽肠道微生物群.
- 对抗微生物 (AMP) 和抗氧化基因 (SOD,DUOX,NOX) 的基因表达分析.
- 用Bacillus thuringiensis (Bt) 和Boeveria bassiana (Bb) 进行病原体挑战测定.
主要成果:
- 微生物群枯竭减少了阿塔辛,防御蛋白和SOD基因表达.
- 微生物群枯竭的幼虫对Bt和Bb的脆弱性增加.
- 内血细胞内微生物注射抑制了肠道微生物群,表明幽默和肠道免疫之间存在联系.
结论:
- 来自微生物群的信号对于原始化昆虫的先天免疫路径至关重要.
- 准肠道微生物群可以提高害虫对生物控制剂的敏感性.
- 微生物组操纵为改善微生物害虫控制提供了一个有希望的策略.
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