在焦虑和睡眠质量之间的关联中,前额外激活和抑制性能:fNIRS调查
Bingyan Lin1, Difan Wang2, Maya J Schroevers3
1Department of Primary and Long-term Care, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.
Journal of affective disorders
|January 28, 2026
概括
焦虑与睡眠质量不佳有关,原因是前额叶皮层 (PFC) 活化减少和抑制控制受损. 增强抑制功能可能会改善焦虑症患者的睡眠.
科学领域:
- 神经科学是一个神经科学.
- 临床心理学 临床心理学
- 认知科学 认知科学
背景情况:
- 焦虑和睡眠障碍往往是并发症,但根本的神经和认知机制尚未完全理解.
- 这项研究调查了前额叶皮层 (PFC) 激活和抑制控制在焦虑和睡眠质量之间的关系中的作用.
研究的目的:
- 检查神经认知途径,将焦虑障碍与睡眠障碍联系起来.
- 评估PFC激活和抑制性能在这种关系中的中介作用.
主要方法:
- 181名参与者 (91名焦虑症患者,90名健康对照) 进行了Stroop任务.
- 功能近红外谱学 (fNIRS) 在任务期间测量了PFC激活.
- 焦虑和睡眠质量使用Zung的自我评价焦虑量表 (SAS) 和匹兹堡睡眠质量指数 (PSQI) 进行评估.
主要成果:
- 与对照人群相比,焦虑患者的睡眠状况较差,抑制能力受损,PFC激活率降低.
- 焦虑与睡眠不足和抑制受损正相关,与PFC激活负相关.
- 背侧PFC (DLPFC) 激活和抑制性能顺序介导了焦虑和睡眠质量之间的联系.
结论:
- DLPFC激活和抑制控制是焦虑和睡眠质量之间的关键神经认知调解者.
- 针对抑制功能的干预措施可以改善焦虑症患者的睡眠和功能.
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