来自Pseudomonas deceptionensis的甲氨酸 γ-Lyase的改进和工程,基于分子动力学模拟和适应性分析,用于抗瘤应用

Lili Wu1, Sen Zou2, Xuemin Li1

  • 1The Third People's Hospital of Hefei in Anhui Province, Heifei, China.

概括

改造的氨酸γ-酶 (MGL) 显示了增强的抗癌性质. 分子动力学和人工智能模型改善了酶活性和稳定性,使其成为结直肠癌的有希望的治疗候选者.

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